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Bone RA, Lowndes MP, Raineri S, R Riveiro A, Lundregan SL, Dall M, Sulek K, Romero JAH, Malzard L, Koigi S, Heckenbach IJ, Solis-Mezarino V, Völker-Albert M, Vasilopoulou CG, Meier F, Trusina A, Mann M, L Nielsen M, Treebak JT, Brickman JM. Altering metabolism programs cell identity via NAD<sup>+</sup>-dependent deacetylation. EMBO J April 2025 10.1038/s44318-025-00417-0 EuropePMC
Van Nerum K, Wenzel A, Argemi-Muntadas L, Kafkia E, Drews A, Brun IS, Lavro V, Roelofsen A, Stamidis N, Arnal SB, Zhao C, di Sanzo S, Völker-Albert M, Petropoulos S, Moritz T, Żylicz JJ. α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells. Nat Cell Biol April 2025 10.1038/s41556-025-01658-1 EuropePMC
Hammerhøj AD, Boye TL, Yao J, Hausmann A, Kellermann L, Maciag GJ, Sandelin A, Steenholdt C, Jensen KB, Nielsen OH. Inflamed Intestinal Epithelial Cells From Patients With Ulcerative Colitis Restore a Noninflamed Transcriptional Profile Upon In Vitro Expansion. Lab Invest April 2025 10.1016/j.labinv.2025.104172 EuropePMC
Urso FG, Del Prete S, Foucher C, Barberis M, Carriero F, Bart A. Use of a 3D Model with Reconstructed Human Epidermis Infected with Fungi and Covered with a Bovine Nail to Simulate Onychomycosis and to Evaluate the Effects of Antifungal Agents. J Fungi (Basel) April 2025 10.3390/jof11040285 EuropePMC
Gil CRE, Lund J, Żylicz JJ, Ranea-Robles P, Sørensen TIA, Clemmensen C. Food insecurity promotes adiposity in mice. Obesity (Silver Spring) March 2025 10.1002/oby.24259 EuropePMC
Kroon S, Malcic D, Weidert L, Bircher L, Boldt L, Christen P, Kiefer P, Sintsova A, Nguyen BD, Barthel M, Steiger Y, Clerc M, Herzog MK, Chen C, Gül E, Guery B, Slack E, Sunagawa S, Vorholt JA, Maier L, Lacroix C, Hausmann A, Hardt WD. Sublethal systemic LPS in mice enables gut-luminal pathogens to bloom through oxygen species-mediated microbiota inhibition. Nat Commun March 2025 10.1038/s41467-025-57979-0 EuropePMC
Iqbal S, Andersson S, Nesta E, Pentinmikko N, Kumar A, Kumar Jha S, Borshagovski D, Webb A, Gebert N, Viitala EW, Ritchie A, Scharaw S, Kuuluvainen E, Larsen HL, Saarinen T, Juuti A, Ristimäki A, Jeltsch M, Ori A, Varjosalo M, Pietiläinen KH, Ollila S, Jensen KB, Oudhoff MJ, Katajisto P. Fetal-like reversion in the regenerating intestine is regulated by mesenchymal asporin. Cell Stem Cell March 2025 10.1016/j.stem.2025.02.009 EuropePMC
Tiemann U, Tian C, Hermann F, Proks M, Skovgaard E, Kulik I, Di Y, Sedzinski J, Semb H. Pancreatic alpha and beta cell fate choice is directed by apical-basal polarity dynamics. Dev Cell March 2025 10.1016/j.devcel.2025.02.008 EuropePMC
Holm Nygaard A, Schörling AL, Abay-Nørgaard Z, Hänninen E, Li Y, Ramón Santonja A, Rathore GS, Salvador A, Rusimbi C, Lauritzen KB, Zhang Y, Kirkeby A. Patterning effects of FGF17 and cAMP on generation of dopaminergic progenitors for cell replacement therapy in Parkinson's disease. Stem Cells March 2025 10.1093/stmcls/sxaf004 EuropePMC
Andersen MS, Ulyanchenko S, Schweiger PJ, Hannezo E, Simons BD, Jensen KB. Spatiotemporal Switches in Progenitor Cell Fate Govern Upper Hair Follicle Growth and Maintenance. J Invest Dermatol February 2025 10.1016/j.jid.2025.01.034 EuropePMC
Seah MKY, Han BY, Huang Y, Rasmussen LJH, Stäubli AJ, Bello-Rodríguez J, Chan AC, Gasnier M, Wollmann H, Guccione E, Messerschmidt DM. Maternal PRDM10 activates essential genes for oocyte-to-embryo transition. Nat Commun February 2025 10.1038/s41467-025-56991-8 EuropePMC
Zhang X, Tao L, Nygaard AH, Dong Y, Groves T, Hong X, Goddard CM, He C, Postnov D, Allodi I, Lauritzen MJ, Cai C. Aging alters calcium signaling in vascular mural cells and drives remodeling of neurovascular coupling in the awake brain. J Cereb Blood Flow Metab February 2025 10.1177/0271678x251320455 EuropePMC
Hölzenspies JJ, Sengupta D, Bickmore WA, Brickman JM, Illingworth RS. PRC2 promotes canalisation during endodermal differentiation. PLoS Genet January 2025 10.1371/journal.pgen.1011584 EuropePMC
Banjac I, Maimets M, Tsang IHC, Dioli M, Hansen SL, Krizic K, Bressan RB, Lövkvist C, Jensen KB. Fate mapping in mouse demonstrates early secretory differentiation directly from Lgr5+ intestinal stem cells. Dev Cell January 2025 10.1016/j.devcel.2024.12.023 EuropePMC
Kirkeby A, Main H, Carpenter M. Pluripotent stem-cell-derived therapies in clinical trial: A 2025 update. Cell Stem Cell January 2025 10.1016/j.stem.2024.12.005 EuropePMC
Tesoriere A, Ghirardo R, Terrin F, Sernesi F, Meneghetti G, Dalla Valle L, Dinarello A, Argenton F. Tail Fin Regeneration in Zebrafish: The Role of Non-canonical Crosstalk Between STAT3 and Vitamin D Pathway. Int J Biol Sci January 2025 10.7150/ijbs.96400 EuropePMC
Tine Friis, AuthorCorresponding authorInternal person, Louise Whiteley, AuthorInternal person, Adam Bencard, AuthorInternal person The allure of microbiome research Humanities and Social Sciences Communications January 2025 10.1057/s41599-025-04833-9 Excel
Hoeyer K, Borsch AS, Jensen KB, Kirkeby A, Steenholdt C, Wadmann S. Risk-based pricing models and the role they might play in patients' access to new stem cell therapies. Regen Med December 2024 10.1080/17460751.2024.2441642 EuropePMC
Kohler KT, Kim J, Villadsen R, Rønnov-Jessen L, Petersen OW. Oncogene activated human breast luminal progenitors contribute basally located myoepithelial cells. Breast Cancer Res December 2024 10.1186/s13058-024-01939-x EuropePMC
Das S, Parigi SM, Luo X, Fransson J, Kern BC, Okhovat A, Diaz OE, Sorini C, Czarnewski P, Webb AT, Morales RA, Lebon S, Monasterio G, Castillo F, Tripathi KP, He N, Pelczar P, Schaltenberg N, De la Fuente M, López-Köstner F, Nylén S, Larsen HL, Kuiper R, Antonson P, Hermoso MA, Huber S, Biton M, Scharaw S, Gustafsson JÅ, Katajisto P, Villablanca EJ. Liver X receptor unlinks intestinal regeneration and tumorigenesis. Nature November 2024 10.1038/s41586-024-08247-6 EuropePMC
van den Berg CW, Dumas SJ, Little MH, Rabelink TJ. Challenges in maturation and integration of kidney organoids for stem cell-based renal replacement therapy. Kidney Int November 2024 10.1016/j.kint.2024.10.028 EuropePMC
Proks M, Salehin N, Brickman JM. Deep learning-based models for preimplantation mouse and human embryos based on single-cell RNA sequencing. Nat Methods November 2024 10.1038/s41592-024-02511-3 EuropePMC
Banhos Danneskiold-Samsøe N, Kavi D, Jude KM, Nissen SB, Wat LW, Coassolo L, Zhao M, Santana-Oikawa GA, Broido BB, Garcia KC, Svensson KJ. AlphaFold2 enables accurate deorphanization of ligands to single-pass receptors. Cell Syst November 2024 10.1016/j.cels.2024.10.004 EuropePMC
Perera M, Brickman JM. Common modes of ERK induction resolve into context-specific signalling via emergent networks and cell-type-specific transcriptional repression. Development October 2024 10.1242/dev.202842 EuropePMC
Romani P, Benedetti G, Cusan M, Arboit M, Cirillo C, Wu X, Rouni G, Kostourou V, Aragona M, Giampietro C, Grumati P, Martello G, Dupont S. Mitochondrial mechanotransduction through MIEF1 coordinates the nuclear response to forces. Nat Cell Biol October 2024 10.1038/s41556-024-01527-3 EuropePMC
Storm P, Zhang Y, Nilsson F, Fiorenzano A, Krausse N, Åkerblom M, Davidsson M, Yuan J, Kirkeby A, Björklund T, Parmar M. Lineage tracing of stem cell-derived dopamine grafts in a Parkinson's model reveals shared origin of all graft-derived cells. Sci Adv October 2024 10.1126/sciadv.adn3057 EuropePMC
Kellermann L, Hansen SL, Maciag G, Granau AM, Johansen JV, Teves JM, Bressan RB, Pedersen MT, Soendergaard C, Baattrup AM, Hammerhøj A, Riis LB, Gubatan J, Jensen KB, Nielsen OH. Influence of Vitamin D Receptor Signalling and Vitamin D on Colonic Epithelial Cell Fate Decisions in Ulcerative Colitis. J Crohns Colitis October 2024 10.1093/ecco-jcc/jjae074 EuropePMC
Siriwardena D, Munger C, Penfold C, Kohler TN, Weberling A, Linneberg-Agerholm M, Slatery E, Ellermann AL, Bergmann S, Clark SJ, Rawlings TM, Brickman JM, Reik W, Brosens JJ, Zernicka-Goetz M, Sasaki E, Behr R, Hollfelder F, Boroviak TE. Marmoset and human trophoblast stem cells differ in signaling requirements and recapitulate divergent modes of trophoblast invasion. Cell Stem Cell September 2024 10.1016/j.stem.2024.09.004 EuropePMC
Maciag G, Hansen SL, Krizic K, Kellermann L, Inventor Zøylner MJ, Ulyanchenko S, Maimets M, Baattrup AM, Riis LB, Khodosevich K, Sato T, Bressan RB, Nielsen OH, Jensen KB. JAK/STAT signaling promotes the emergence of unique cell states in ulcerative colitis. Stem Cell Reports July 2024 10.1016/j.stemcr.2024.06.006 EuropePMC
Xu X, Nielsen BF, Sneppen K. Self-inhibiting percolation and viral spreading in epithelial tissue. Elife June 2024 10.7554/elife.94056 EuropePMC
Funa NS, Mjoseng HK, de Lichtenberg KH, Raineri S, Esen D, Egeskov-Madsen AR, Quaranta R, Jørgensen MC, Hansen MS, van Cuyl Kuylenstierna J, Jensen KB, Miao Y, Garcia KC, Seymour PA, Serup P. TGF-β modulates cell fate in human ES cell-derived foregut endoderm by inhibiting Wnt and BMP signaling. Stem Cell Reports June 2024 10.1016/j.stemcr.2024.05.010 EuropePMC
Linneberg-Agerholm M, Sell AC, Redó-Riveiro A, Perera M, Proks M, Knudsen TE, Barral A, Manzanares M, Brickman JM. The primitive endoderm supports lineage plasticity to enable regulative development. Cell June 2024 10.1016/j.cell.2024.05.051 EuropePMC
Hammerhøj A, Chakravarti D, Sato T, Jensen KB, Nielsen OH. Organoids as regenerative medicine for inflammatory bowel disease. iScience May 2024 10.1016/j.isci.2024.110118 EuropePMC
Kuhn TM, Paulsen M, Cuylen-Haering S. Accessible high-speed image-activated cell sorting. Trends Cell Biol May 2024 10.1016/j.tcb.2024.04.007 EuropePMC
Rifes P, Kajtez J, Christiansen JR, Schörling A, Rathore GS, Wolf DA, Heuer A, Kirkeby A. Forced LMX1A expression induces dorsal neural fates and disrupts patterning of human embryonic stem cells into ventral midbrain dopaminergic neurons. Stem Cell Reports May 2024 10.1016/j.stemcr.2024.04.010 EuropePMC
Hölzenspies JJ, Sengupta D, Bickmore WA, Brickman JM, Illingworth RS. PRC2 Promotes Canalisation During Endodermal Differentiation None April 2024 10.1101/2024.04.23.590736 EuropePMC
Brañas Casas R, Zuppardo A, Risato G, Dinarello A, Celeghin R, Fontana C, Grelloni E, Gilea AI, Viscomi C, Rasola A, Dalla Valle L, Lodi T, Baruffini E, Facchinello N, Argenton F, Tiso N. Zebrafish polg2 knock-out recapitulates human POLG-disorders; implications for drug treatment. Cell Death Dis April 2024 10.1038/s41419-024-06622-9 EuropePMC
Dardano M, Lebek T, H C Tsang I. Exploring stem cell frontiers: definitions, challenges, and perspectives for regenerative medicine. Biol Open April 2024 10.1242/bio.060245 EuropePMC
Christiansen JR, Kirkeby A. Clinical translation of pluripotent stem cell-based therapies: successes and challenges. Development April 2024 10.1242/dev.202067 EuropePMC
Gaballa JM, Højen JF, De Graaf DM, Amo-Aparicio J, Marchetti C, Cavalli G, Dinarello A, Li S, Corbisiero MF, Tengesdal IW, Redzic JS, Azam T, Webber WS, Pankratz KA, May MJ, Cominelli F, Eisenmesser EZ, Kim S, Dinarello CA, Boraschi D. International nomenclature guidelines for the IL-1 family of cytokines and receptors. Nat Immunol April 2024 10.1038/s41590-024-01777-1 EuropePMC
Novoa JJ, Westra IM, Steeneveld E, Fonseca Neves N, Arendzen CH, Rajaei B, Grundeken E, Yildiz M, van der Valk W, Salvador A, Carlotti F, Dijkers PF, Locher H, van den Berg CW, Raymond KI, Kirkeby A, Mummery CL, Rabelink TJ, Freund C, Meij P, Wieles B. Good Manufacturing Practice-compliant human induced pluripotent stem cells: from bench to putative clinical products. Cytotherapy March 2024 10.1016/j.jcyt.2024.02.021 EuropePMC
Vanslambrouck JM, Neil JA, Rudraraju R, Mah S, Tan KS, Groenewegen E, Forbes TA, Karavendzas K, Elliott DA, Porrello ER, Subbarao K, Little MH. Kidney organoids reveal redundancy in viral entry pathways during ACE2-dependent SARS-CoV-2 infection. J Virol February 2024 10.1128/jvi.01802-23 EuropePMC
Sanchís-Calleja F, Jain A, He Z, Okamoto R, Rusimbi C, Rifes P, Rathore GS, Santel M, Janssens J, Seimiya M, Fleck JS, Kirkeby A, Camp JG, Treutlein B. Decoding morphogen patterning of human neural organoids with a multiplexed single-cell transcriptomic screen None February 2024 10.1101/2024.02.08.579413 EuropePMC
Hausmann A, Steenholdt C, Nielsen OH, Jensen KB. Immune cell-derived signals governing epithelial phenotypes in homeostasis and inflammation. Trends Mol Med February 2024 10.1016/j.molmed.2024.01.001 EuropePMC
Hoeyer K, Couturier A, Barawi K, Drew C, Grundtvig A, Lane E, Munk AK, Whiteley LE, Munsie M. Searching for information about stem cells online in an age of artificial intelligence: How should the stem cell community respond? Stem Cell Reports January 2024 10.1016/j.stemcr.2023.12.009 EuropePMC
Redó-Riveiro A, Al-Mousawi J, Linneberg-Agerholm M, Proks M, Perera M, Salehin N, Brickman JM. Transcription factor co-expression mediates lineage priming for embryonic and extra-embryonic differentiation. Stem Cell Reports January 2024 10.1016/j.stemcr.2023.12.002 EuropePMC
Paulsen MS. Image-Enabled Cell Sorting Using the BD CellView Technology. Methods Mol Biol January 2024 10.1007/978-1-0716-3738-8_8 EuropePMC
Tine Friis, AuthorInternal person, Louise Whiteley, AuthorInternal person Making voices January 2024 10.1007/978-3-031-44119-6_18 Excel
Brandão KO, Meraviglia V, Salvatori D, Cao X, Sala L, Yiangou L, Mol MP, Bellin M, Mummery CL, Davis RP. Gain of chromosome region 1q31.3 in human iPSCs confers growth advantage and alters contraction in derivative cardiomyocytes None December 2023 10.1101/2023.12.11.571144 EuropePMC
Rifes P, Isaksson M, Rusimbi C, Ramón Santonja A, Nelander J, Laurell T, Kirkeby A. Identifying secreted biomarkers of dopaminergic ventral midbrain progenitor cells. Stem Cell Res Ther December 2023 10.1186/s13287-023-03580-5 EuropePMC
Bornholdt J, Müller CV, Nielsen MJ, Strickertsson J, Rago D, Chen Y, Maciag G, Skov J, Wellejus A, Schweiger PJ, Hansen SL, Broholm C, Gögenur I, Maimets M, Sloth S, Hendel J, Baker A, Sandelin A, Jensen KB. Detecting host responses to microbial stimulation using primary epithelial organoids. Gut Microbes November 2023 10.1080/19490976.2023.2281012 EuropePMC
Xu Q, Halle L, Hediyeh-zadeh S, Kuijs M, Kilik U, Yu Q, Frum T, Adam L, Parikh S, Gander M, Kfuri-Rubens R, Klein D, He Z, Fleck JS, Oost K, Kahnwald M, Barbiero S, Mitrofanova O, Maciag G, Jensen KB, Lutolf M, Liberali P, Beumer J, Spence JR, Treutlein B, Theis FJ, Camp JG. An integrated transcriptomic cell atlas of human endoderm-derived organoids None November 2023 10.1101/2023.11.20.567825 EuropePMC
Song S, Cho B, Weiner AT, Nissen SB, Ojeda Naharros I, Sanchez Bosch P, Suyama K, Hu Y, He L, Svinkina T, Udeshi ND, Carr SA, Perrimon N, Axelrod JD. Protein phosphatase 1 regulates core PCP signaling. EMBO Rep November 2023 10.15252/embr.202356997 EuropePMC
Garza R, Sharma Y, Atacho DAM, Thiruvalluvan A, Abu Hamdeh S, Jönsson ME, Horvath V, Adami A, Ingelsson M, Jern P, Hammell MG, Englund E, Kirkeby A, Jakobsson J, Marklund N. Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia. Cell Rep November 2023 10.1016/j.celrep.2023.113395 EuropePMC
Glymenaki M, Hahn AM, Hausmann A, Kempkes RWM, Kilic G, Kulsvehagen L, Mooslechner AA, Mossadegh-Keller N, Nabhan M, Bechara R, yEFIS Task Force. Young EFIS: Three years of progress - Reflecting on achievements and embracing new horizons. Eur J Immunol October 2023 10.1002/eji.202350749 EuropePMC
Kim H, Kumar A, Lövkvist C, Palma AM, Martin P, Kim J, Bhoopathi P, Trevino J, Fisher P, Madan E, Gogna R, Won KJ. CellNeighborEX: deciphering neighbor-dependent gene expression from spatial transcriptomics data. Mol Syst Biol October 2023 10.15252/msb.202311670 EuropePMC
Kirkeby A, Nelander J, Hoban DB, Rogelius N, Bjartmarz H, Novo Nordisk Cell Therapy R&D, Storm P, Fiorenzano A, Adler AF, Vale S, Mudannayake J, Zhang Y, Cardoso T, Mattsson B, Landau AM, Glud AN, Sørensen JC, Lillethorup TP, Lowdell M, Carvalho C, Bain O, van Vliet T, Lindvall O, Björklund A, Harry B, Cutting E, Widner H, Paul G, Barker RA, Parmar M. Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD. Cell Stem Cell October 2023 10.1016/j.stem.2023.08.014 EuropePMC
Perera M, Brickman JM. In vitro models of human hypoblast and mouse primitive endoderm. Curr Opin Genet Dev September 2023 10.1016/j.gde.2023.102115 EuropePMC
Vanslambrouck JM, Tan KS, Mah S, Little MH. Generation of proximal tubule-enhanced kidney organoids from human pluripotent stem cells. Nat Protoc September 2023 10.1038/s41596-023-00880-1 EuropePMC
Wenger A, Biran A, Alcaraz N, Redó-Riveiro A, Sell AC, Krautz R, Flury V, Reverón-Gómez N, Solis-Mezarino V, Völker-Albert M, Imhof A, Andersson R, Brickman JM, Groth A. Symmetric inheritance of parental histones governs epigenome maintenance and embryonic stem cell identity. Nat Genet September 2023 10.1038/s41588-023-01476-x EuropePMC
Ludwig TE, Andrews PW, Barbaric I, Benvenisty N, Bhattacharyya A, Crook JM, Daheron LM, Draper JS, Healy LE, Huch M, Inamdar MS, Jensen KB, Kurtz A, Lancaster MA, Liberali P, Lutolf MP, Mummery CL, Pera MF, Sato Y, Shimasaki N, Smith AG, Song J, Spits C, Stacey G, Wells CA, Zhao T, Mosher JT. ISSCR standards for the use of human stem cells in basic research. Stem Cell Reports September 2023 10.1016/j.stemcr.2023.08.003 EuropePMC
Knudsen TE, Hamilton WB, Proks M, Lykkegaard M, Linneberg-Agerholm M, Nielsen AV, Perera M, Malzard LL, Trusina A, Brickman JM. A bipartite function of ESRRB can integrate signaling over time to balance self-renewal and differentiation. Cell Syst August 2023 10.1016/j.cels.2023.07.008 EuropePMC
Maimets M. Help! I need a WNT antibody. Help! Not just any antibody. Cell Chem Biol August 2023 10.1016/j.chembiol.2023.07.007 EuropePMC
Häfner SJ, Jansson MD, Altinel K, Andersen KL, Abay-Nørgaard Z, Ménard P, Fontenas M, Sørensen DM, Gay DM, Arendrup FS, Tehler D, Krogh N, Nielsen H, Kraushar ML, Kirkeby A, Lund AH. Ribosomal RNA 2'-O-methylation dynamics impact cell fate decisions. Dev Cell July 2023 10.1016/j.devcel.2023.06.007 EuropePMC
Mullari M, Fossat N, Skotte NH, Asenjo-Martinez A, Humphreys DT, Bukh J, Kirkeby A, Scheel TKH, Nielsen ML. Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington's disease. Nat Commun July 2023 10.1038/s41467-023-39936-x EuropePMC
Pikkupeura LM, Bressan RB, Guiu J, Chen Y, Maimets M, Mayer D, Schweiger PJ, Hansen SL, Maciag GJ, Larsen HL, Lõhmussaar K, Pedersen MT, Teves JMY, Bornholdt J, Benes V, Sandelin A, Jensen KB. Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation. Sci Adv July 2023 10.1126/sciadv.adf9460 EuropePMC
Hansen SL, Larsen HL, Pikkupeura LM, Maciag G, Guiu J, Müller I, Clement DL, Mueller C, Johansen JV, Helin K, Lerdrup M, Jensen KB. An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate. Sci Adv July 2023 10.1126/sciadv.adg4055 EuropePMC
Seymour PA, Serup P. Differential use of the Nkx2.2 NK2 domain in developing pancreatic islets and neurons. Genes Dev June 2023 10.1101/gad.350895.123 EuropePMC
Jensen KB, Little MH. Organoids are not organs: Sources of variation and misinformation in organoid biology. Stem Cell Reports June 2023 10.1016/j.stemcr.2023.05.009 EuropePMC
Kajtez J, Radeke C, Lind JU, Emnéus J. Microgel-Extracellular Matrix Composite Support for the Embedded 3D Printing of Human Neural Constructs. J Vis Exp May 2023 10.3791/65158 EuropePMC
Lee J, Møller AF, Chae S, Bussek A, Park TJ, Kim Y, Lee HS, Pers TH, Kwon T, Sedzinski J, Natarajan KN. A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development. Sci Adv April 2023 10.1126/sciadv.add5745 EuropePMC
Banjac I, Maimets M, Jensen KB. Maintenance of high-turnover tissues during and beyond homeostasis. Cell Stem Cell April 2023 10.1016/j.stem.2023.03.008 EuropePMC
Stamidis N, Żylicz JJ. RNA-mediated heterochromatin formation at repetitive elements in mammals. EMBO J February 2023 10.15252/embj.2022111717 EuropePMC
Granau AM, Boye TL, Jensen KB, Nielsen OH. Deucravacitinib (Sotyktu™) for plaque psoriasis. Trends Pharmacol Sci February 2023 10.1016/j.tips.2023.01.004 EuropePMC
Wong YF, Kumar Y, Proks M, Herrera JAR, Rothová MM, Monteiro RS, Pozzi S, Jennings RE, Hanley NA, Bickmore WA, Brickman JM. Expansion of ventral foregut is linked to changes in the enhancer landscape for organ-specific differentiation. Nat Cell Biol January 2023 10.1038/s41556-022-01075-8 EuropePMC
Xu X, Seymour PA, Sneppen K, Trusina A, Egeskov-Madsen AR, Jørgensen MC, Jensen MH, Serup P. Jag1-Notch cis-interaction determines cell fate segregation in pancreatic development. Nat Commun January 2023 10.1038/s41467-023-35963-w EuropePMC
Kim J, Rothová MM, Madan E, Rhee S, Weng G, Palma AM, Liao L, David E, Amit I, Hajkarim MC, Vudatha V, Gutiérrez-García A, Moreno E, Winn R, Trevino J, Fisher PB, Brickman JM, Gogna R, Won KJ. Neighbor-specific gene expression revealed from physically interacting cells during mouse embryonic development. Proc Natl Acad Sci U S A January 2023 10.1073/pnas.2205371120 EuropePMC
Dubonyte U, Asenjo-Martinez A, Werge T, Lage K, Kirkeby A. Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells. Acta Neuropathol Commun December 2022 10.1186/s40478-022-01460-2 EuropePMC
Coassolo L, Liu T, Jung Y, Taylor NP, Zhao M, Charville GW, Nissen SB, Yki-Jarvinen H, Altman RB, Svensson KJ. Mapping transcriptional heterogeneity and metabolic networks in fatty livers at single-cell resolution. iScience December 2022 10.1016/j.isci.2022.105802 EuropePMC
Ventura G, Amiri A, Thiagarajan R, Tolonen M, Doostmohammadi A, Sedzinski J. Multiciliated cells use filopodia to probe tissue mechanics during epithelial integration in vivo. Nat Commun October 2022 10.1038/s41467-022-34165-0 EuropePMC
Pladevall-Morera D, Zylicz JJ. Chromatin as a sensor of metabolic changes during early development. Front Cell Dev Biol October 2022 10.3389/fcell.2022.1014498 EuropePMC
Ventura G, Sedzinski J. Emerging concepts on the mechanical interplay between migrating cells and microenvironment in vivo. Front Cell Dev Biol September 2022 10.3389/fcell.2022.961460 EuropePMC
Dorison A, Ghobrial I, Graham A, Peiris T, Forbes TA, See M, Das M, Saleem MA, Quinlan C, Lawlor KT, Ramialison M, Howden SE, Little MH. Kidney Organoids Generated Using an Allelic Series of NPHS2 Point Variants Reveal Distinct Intracellular Podocin Mistrafficking. J Am Soc Nephrol September 2022 10.1681/asn.2022060707 EuropePMC
Sukparangsi W, Morganti E, Lowndes M, Mayeur H, Weisser M, Hammachi F, Peradziryi H, Roske F, Hölzenspies J, Livigni A, Godard BG, Sugahara F, Kuratani S, Montoya G, Frankenberg SR, Mazan S, Brickman JM. Evolutionary origin of vertebrate OCT4/POU5 functions in supporting pluripotency. Nat Commun September 2022 10.1038/s41467-022-32481-z EuropePMC
Schweiger PJ, Le Bouteiller M, Yui S, Thodberg M, Clement D, Jensen KB. Extracellular Matrix Interactions Provide Tumor Cells With an Escape Mechanism for Commitment to Differentiation. Gastroenterology August 2022 10.1053/j.gastro.2022.08.036 EuropePMC
Perera M, Nissen SB, Proks M, Pozzi S, Monteiro RS, Trusina A, Brickman JM. Transcriptional heterogeneity and cell cycle regulation as central determinants of Primitive Endoderm priming. Elife August 2022 10.7554/elife.78967 EuropePMC
Dorison A, Forbes TA, Little MH. What can we learn from kidney organoids? Kidney Int August 2022 10.1016/j.kint.2022.06.032 EuropePMC
Rothová MM, Nielsen AV, Proks M, Wong YF, Riveiro AR, Linneberg-Agerholm M, David E, Amit I, Trusina A, Brickman JM. Identification of the central intermediate in the extra-embryonic to embryonic endoderm transition through single-cell transcriptomics. Nat Cell Biol June 2022 10.1038/s41556-022-00923-x EuropePMC
Mund A, Coscia F, Kriston A, Hollandi R, Kovács F, Brunner AD, Migh E, Schweizer L, Santos A, Bzorek M, Naimy S, Rahbek-Gjerdrum LM, Dyring-Andersen B, Bulkescher J, Lukas C, Eckert MA, Lengyel E, Gnann C, Lundberg E, Horvath P, Mann M. Deep Visual Proteomics defines single-cell identity and heterogeneity. Nat Biotechnol May 2022 10.1038/s41587-022-01302-5 EuropePMC
Boye TL, Steenholdt C, Jensen KB, Nielsen OH. Molecular Manipulations and Intestinal Stem Cell-Derived Organoids in Inflammatory Bowel Disease. Stem Cells May 2022 10.1093/stmcls/sxac014 EuropePMC

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